![]() T2 - Severe Malapposition and Cardiac Events T1 - Clinical Implications of Poststent Optical Coherence Tomographic Findings ![]() Conclusions: Although most suboptimal OCT findings were not associated with clinical outcomes, a smaller MSA was associated with DoCE, driven mainly by TLR, and significant malapposition with TMV ≥7.0 mm3 was associated with more MSE after PCI.", Follow-up OCT at 3, 6, or 9 months after PCI showed that poststent TMV ≥7.0 mm3 was related to a greater occurrence of late malapposition and uncovered struts. Malapposition with TMV ≥7.0 mm3 was found to be an independent predictor of MSE (HR: 6.12 p = 0.003). A smaller minimal stent area (MSA) was identified as an independent predictor for DoCE (hazard ratio : 1.20 : 1.00 to 1.43] p = 0.045). However, patients with significant malapposition (total malapposition volume ≥7.0 mm3] exhibited more frequent MSE. The incidence rates of stent edge dissection, tissue prolapse, thrombus, and malapposition after intervention were not associated with occurrence of DoCE. Results: The median follow-up period was 43.0 months (interquartile range 21.4 to 56.0 months). Significant malapposition criteria associated with major safety events (MSE) were also investigated, such as cardiac death, target vessel-related MI, or stent thrombosis. Poststent OCT findings were assessed to identify predictors of device-oriented clinical endpoints (DoCE), including cardiac death, target vessel-related myocardial infarction (MI) or stent thrombosis, and target lesion revascularization (TLR). All patients underwent implantation of drug-eluting stents. Methods: Of the patients registered in the Yonsei OCT registry, a total of 1,290 patients with 1,348 lesions, who underwent OCT immediately poststenting, were consecutively enrolled for this study. Background: Suboptimal OCT findings following percutaneous coronary intervention (PCI) are highly prevalent however, their clinical implications remain controversial. Conclusions: Although most suboptimal OCT findings were not associated with clinical outcomes, a smaller MSA was associated with DoCE, driven mainly by TLR, and significant malapposition with TMV ≥7.0 mm 3 was associated with more MSE after PCI.Ībstract = "Objectives: This study sought to evaluate the impact of poststent optical coherence tomography (OCT) findings, including severe malapposition, on long-term clinical outcomes. Follow-up OCT at 3, 6, or 9 months after PCI showed that poststent TMV ≥7.0 mm 3 was related to a greater occurrence of late malapposition and uncovered struts. Malapposition with TMV ≥7.0 mm 3 was found to be an independent predictor of MSE (HR: 6.12 p = 0.003). However, patients with significant malapposition (total malapposition volume ≥7.0 mm 3] exhibited more frequent MSE. ![]() Objectives: This study sought to evaluate the impact of poststent optical coherence tomography (OCT) findings, including severe malapposition, on long-term clinical outcomes. ![]()
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